VIRULENCE IN STAPHYLOCOCCUS AUREUS

A METHICILLIN RESISTANT SKIN MICROBE

 

S.aureus a potent bacteria that cause serious life-threatening skin infections. It is a gram-positive round-shaped bacterium. It causes infections commonly in the respiratory tract, nose other than skin. The infections by this organism are often life-threatening in people with weaker immunity.

The organism is the most aggressive and multiple drug-resistant if our body does not have sufficient resistance.

Moreover, the organism is anaerobic and does not need oxygen for its growth.

In normal healthy people with sufficient immunity power it may cause skin infections such as abscess, and sinusitis which may not be so serious and even in some people with strong health and immunity it may present without expressing any common pathogenic symptoms.AIDS patients or any immunity compromising people the organism causes serious life-threatening effects.

But a recent study revealed that a seriously aggressive potent virulent strain of S.aureus known as Community Associated Methicillin-Resistant S.aureus (CA-MRSA) is emerging as a life-threatening bacteria around the globe even to the healthy people.
But the researches open a clear way to find out a solution to curb the epidemic. Methicillin the wide spectrum strong antibiotic among the penicillin group becomes inactive against these resistant strains.
The reason is increased insertion of long-chain sugar polymers, the cell wall teichoic acids on the outer cell which make the cell wall envelope of the organism more resistant to antibiotics.
This study result may help the scientists in the future to depress such modification in order to suppress the virulence and resistance.
Now the scientists from the Interfaculty Institute of Microbiology and Infection Medicine, Tubingen (IMIT), and the German Center for Infection Research (DZIF) have been able to decipher the secrets of the cell wall modifications of the organism to pave the way for find out a solution for this problem.